Peptide-rich extracts from spent yeast waste streams as a source of bioactive compounds for the nutraceutical market

Spent yeast is one of the main fermentation process by-products and several bioactive ingredients have been extracted from it, such as mannans β-glucans. These extraction processes generate waste streams rich in protein, that can still be used to produce peptide-rich extracts. This work describes use a scalable low-cost obtain peptide extracts circular economy concept. Peptide fractions produced contained 48.3 86.4% protein ( w /w) essential amino acids amounts higher than those defined by FAO WHO references. Regarding their properties, exhibited strong antihypertensive antioxidant activities. Furthermore, an inhibition 62.0–71.3% HMG-CoA reductase was observed, feature hereby described for first time, thus stating cholesterol-lowering capacity peptides. In conclusion, due combined nutritional characteristics, are good candidates dietary supplementation functional foods. • peptides were studied potential ingredient diet supplement. A sustainable, fractions. Fractions consisted small with acid balance. Strong recorded obtained For activities reported on protein.